Cargando…

Biocatalysis: Enzymatic Synthesis for Industrial Applications

Biocatalysis has found numerous applications in various fields as an alternative to chemical catalysis. The use of enzymes in organic synthesis, especially to make chiral compounds for pharmaceuticals as well for the flavors and fragrance industry, are the most prominent examples. In addition, bioca...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Shuke, Snajdrova, Radka, Moore, Jeffrey C., Baldenius, Kai, Bornscheuer, Uwe T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818486/
https://www.ncbi.nlm.nih.gov/pubmed/32558088
http://dx.doi.org/10.1002/anie.202006648
_version_ 1783638846163910656
author Wu, Shuke
Snajdrova, Radka
Moore, Jeffrey C.
Baldenius, Kai
Bornscheuer, Uwe T.
author_facet Wu, Shuke
Snajdrova, Radka
Moore, Jeffrey C.
Baldenius, Kai
Bornscheuer, Uwe T.
author_sort Wu, Shuke
collection PubMed
description Biocatalysis has found numerous applications in various fields as an alternative to chemical catalysis. The use of enzymes in organic synthesis, especially to make chiral compounds for pharmaceuticals as well for the flavors and fragrance industry, are the most prominent examples. In addition, biocatalysts are used on a large scale to make specialty and even bulk chemicals. This review intends to give illustrative examples in this field with a special focus on scalable chemical production using enzymes. It also discusses the opportunities and limitations of enzymatic syntheses using distinct examples and provides an outlook on emerging enzyme classes.
format Online
Article
Text
id pubmed-7818486
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-78184862021-01-29 Biocatalysis: Enzymatic Synthesis for Industrial Applications Wu, Shuke Snajdrova, Radka Moore, Jeffrey C. Baldenius, Kai Bornscheuer, Uwe T. Angew Chem Int Ed Engl Reviews Biocatalysis has found numerous applications in various fields as an alternative to chemical catalysis. The use of enzymes in organic synthesis, especially to make chiral compounds for pharmaceuticals as well for the flavors and fragrance industry, are the most prominent examples. In addition, biocatalysts are used on a large scale to make specialty and even bulk chemicals. This review intends to give illustrative examples in this field with a special focus on scalable chemical production using enzymes. It also discusses the opportunities and limitations of enzymatic syntheses using distinct examples and provides an outlook on emerging enzyme classes. John Wiley and Sons Inc. 2020-08-17 2021-01-04 /pmc/articles/PMC7818486/ /pubmed/32558088 http://dx.doi.org/10.1002/anie.202006648 Text en © 2020 The Authors. Published by Wiley-VCH GmbH This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Reviews
Wu, Shuke
Snajdrova, Radka
Moore, Jeffrey C.
Baldenius, Kai
Bornscheuer, Uwe T.
Biocatalysis: Enzymatic Synthesis for Industrial Applications
title Biocatalysis: Enzymatic Synthesis for Industrial Applications
title_full Biocatalysis: Enzymatic Synthesis for Industrial Applications
title_fullStr Biocatalysis: Enzymatic Synthesis for Industrial Applications
title_full_unstemmed Biocatalysis: Enzymatic Synthesis for Industrial Applications
title_short Biocatalysis: Enzymatic Synthesis for Industrial Applications
title_sort biocatalysis: enzymatic synthesis for industrial applications
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818486/
https://www.ncbi.nlm.nih.gov/pubmed/32558088
http://dx.doi.org/10.1002/anie.202006648
work_keys_str_mv AT wushuke biocatalysisenzymaticsynthesisforindustrialapplications
AT snajdrovaradka biocatalysisenzymaticsynthesisforindustrialapplications
AT moorejeffreyc biocatalysisenzymaticsynthesisforindustrialapplications
AT baldeniuskai biocatalysisenzymaticsynthesisforindustrialapplications
AT bornscheueruwet biocatalysisenzymaticsynthesisforindustrialapplications