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Biocatalysis: Enzymatic Synthesis for Industrial Applications
Biocatalysis has found numerous applications in various fields as an alternative to chemical catalysis. The use of enzymes in organic synthesis, especially to make chiral compounds for pharmaceuticals as well for the flavors and fragrance industry, are the most prominent examples. In addition, bioca...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818486/ https://www.ncbi.nlm.nih.gov/pubmed/32558088 http://dx.doi.org/10.1002/anie.202006648 |
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author | Wu, Shuke Snajdrova, Radka Moore, Jeffrey C. Baldenius, Kai Bornscheuer, Uwe T. |
author_facet | Wu, Shuke Snajdrova, Radka Moore, Jeffrey C. Baldenius, Kai Bornscheuer, Uwe T. |
author_sort | Wu, Shuke |
collection | PubMed |
description | Biocatalysis has found numerous applications in various fields as an alternative to chemical catalysis. The use of enzymes in organic synthesis, especially to make chiral compounds for pharmaceuticals as well for the flavors and fragrance industry, are the most prominent examples. In addition, biocatalysts are used on a large scale to make specialty and even bulk chemicals. This review intends to give illustrative examples in this field with a special focus on scalable chemical production using enzymes. It also discusses the opportunities and limitations of enzymatic syntheses using distinct examples and provides an outlook on emerging enzyme classes. |
format | Online Article Text |
id | pubmed-7818486 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-78184862021-01-29 Biocatalysis: Enzymatic Synthesis for Industrial Applications Wu, Shuke Snajdrova, Radka Moore, Jeffrey C. Baldenius, Kai Bornscheuer, Uwe T. Angew Chem Int Ed Engl Reviews Biocatalysis has found numerous applications in various fields as an alternative to chemical catalysis. The use of enzymes in organic synthesis, especially to make chiral compounds for pharmaceuticals as well for the flavors and fragrance industry, are the most prominent examples. In addition, biocatalysts are used on a large scale to make specialty and even bulk chemicals. This review intends to give illustrative examples in this field with a special focus on scalable chemical production using enzymes. It also discusses the opportunities and limitations of enzymatic syntheses using distinct examples and provides an outlook on emerging enzyme classes. John Wiley and Sons Inc. 2020-08-17 2021-01-04 /pmc/articles/PMC7818486/ /pubmed/32558088 http://dx.doi.org/10.1002/anie.202006648 Text en © 2020 The Authors. Published by Wiley-VCH GmbH This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Reviews Wu, Shuke Snajdrova, Radka Moore, Jeffrey C. Baldenius, Kai Bornscheuer, Uwe T. Biocatalysis: Enzymatic Synthesis for Industrial Applications |
title | Biocatalysis: Enzymatic Synthesis for Industrial Applications |
title_full | Biocatalysis: Enzymatic Synthesis for Industrial Applications |
title_fullStr | Biocatalysis: Enzymatic Synthesis for Industrial Applications |
title_full_unstemmed | Biocatalysis: Enzymatic Synthesis for Industrial Applications |
title_short | Biocatalysis: Enzymatic Synthesis for Industrial Applications |
title_sort | biocatalysis: enzymatic synthesis for industrial applications |
topic | Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818486/ https://www.ncbi.nlm.nih.gov/pubmed/32558088 http://dx.doi.org/10.1002/anie.202006648 |
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