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Evaluation of the Pharmacokinetics, Pharmacodynamics, and Safety of a Single Dose of Emicizumab in Healthy Chinese Subjects

This phase 1, open‐label, single‐center study evaluated the pharmacokinetics (PK), pharmacodynamics, safety, and tolerability of single‐dose emicizumab in healthy Chinese males. Overall, 16 subjects received a single subcutaneous dose of 1‐mg/kg emicizumab. Blood samples were obtained before dosing...

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Detalles Bibliográficos
Autores principales: Li, Haiyan, Zhang, Weijiang, Petry, Claire, Li, Lindong, Fernandez, Elena, Kiialainen, Anna, Feng, Sheng, Hsu, Wanling, Li, Li, Wei, Yudong, Schmitt, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818492/
https://www.ncbi.nlm.nih.gov/pubmed/32433829
http://dx.doi.org/10.1002/cpdd.805

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