Cargando…

Oxidative stress battles neuronal Bcl-xL in a fight to the death

Bcl-xL is a pro-survival protein of the Bcl2 family found in the mitochondrial membrane. Bcl-xL supports growth, development, and maturation of neurons, and it also prevents neuronal death during neurotoxic stimulation. This article reviews the mechanisms and upstream signaling that regulate the act...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Han-A, Broman, Katheryn, Jonas, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818872/
https://www.ncbi.nlm.nih.gov/pubmed/32788441
http://dx.doi.org/10.4103/1673-5374.286946