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TAT-modified serum albumin nanoparticles for sustained-release of tetramethylpyrazine and improved targeting to spinal cord injury

BACKGROUND: Spinal Cord injury (SCI) is a kind of severe traumatic disease. The inflammatory response is a significant feature after SCI. Tetramethylpyrazine (TMP), a perennial herb of umbelliferae, is an alkaloid extracted from ligustici. TMP can inhibit the production of nitric oxide and reduce th...

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Detalles Bibliográficos
Autores principales: Lin, Yan, Wan, Yujie, Du, Xingjie, Li, Jian, Wei, Jun, Li, Ting, Li, Chunhong, Liu, Zhongbing, Zhou, Meiling, Zhong, Zhirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819157/
https://www.ncbi.nlm.nih.gov/pubmed/33478501
http://dx.doi.org/10.1186/s12951-020-00766-4