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HSP22 (HSPB8) positively regulates PGF2α-induced synthesis of interleukin-6 and vascular endothelial growth factor in osteoblasts
BACKGROUND: Heat shock protein 22 (HSP22) belongs to class I of the small HSP family that displays ubiquitous expression in osteoblasts. We previously demonstrated that prostaglandin F2α (PGF2α), a potent bone remodeling factor, induces the synthesis of interleukin-6 (IL-6) and vascular endothelial...
Autores principales: | Kuroyanagi, Gen, Sakai, Go, Otsuka, Takanobu, Yamamoto, Naohiro, Fujita, Kazuhiko, Kawabata, Tetsu, Matsushima-Nishiwaki, Rie, Kozawa, Osamu, Tokuda, Haruhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819160/ https://www.ncbi.nlm.nih.gov/pubmed/33478532 http://dx.doi.org/10.1186/s13018-021-02209-8 |
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