Topical co‐administration of zoledronate with recombinant human bone morphogenetic protein-2 can induce and maintain bone formation in the bone marrow environment

BACKGROUND: Bone morphogenetic proteins (BMPs) induce osteogenesis in various environments. However, when BMPs are used alone in the bone marrow environment, the maintenance of new bone formation is difficult owing to vigorous bone resorption. This is because BMPs stimulate the differentiation of no...

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Detalles Bibliográficos
Autores principales: Ueyama, Hideki, Ohta, Yoichi, Imai, Yuuki, Suzuki, Akinobu, Sugama, Ryo, Minoda, Yukihide, Takaoka, Kunio, Nakamura, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819170/
https://www.ncbi.nlm.nih.gov/pubmed/33472600
http://dx.doi.org/10.1186/s12891-021-03971-w

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