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Blood-based extracellular matrix biomarkers as predictors of survival in patients with metastatic pancreatic ductal adenocarcinoma receiving pegvorhyaluronidase alfa

BACKGROUND: Extensive extracellular matrix (ECM) remodeling is a hallmark of metastatic pancreatic ductal adenocarcinoma (mPDA). We investigated fragments of collagen types III (C3M, PRO-C3), VI (PRO-C6), and VIII (C8-C), and versican (VCANM) in plasma as biomarkers for predicting progression-free s...

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Detalles Bibliográficos
Autores principales:	Wang, Song, Bager, Cecilie L., Karsdal, Morten A., Chondros, Dimitrios, Taverna, Darin, Willumsen, Nicholas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819178/ https://www.ncbi.nlm.nih.gov/pubmed/33478521 http://dx.doi.org/10.1186/s12967-021-02701-z

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