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Prevalence of undiagnosed HIV, hepatitis B, and hepatitis C among patients in an Indian emergency department

OBJECTIVES: HIV, hepatitis B, and hepatitis C remain significant causes of morbidity and mortality in low resource settings. Emergency department (ED)‐based screening has proven effective in decreasing the spread of undiagnosed disease, although such programs are rare in low–middle income countries....

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Autores principales: Pandiselvam, Sathishkumar, Jena, Narendra N., Ghatak‐Roy, Aditi, Dreyer, Nicholas, Naik, Nehal, Blanchard, Janice, Davey, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819266/
https://www.ncbi.nlm.nih.gov/pubmed/33521780
http://dx.doi.org/10.1002/emp2.12328
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author Pandiselvam, Sathishkumar
Jena, Narendra N.
Ghatak‐Roy, Aditi
Dreyer, Nicholas
Naik, Nehal
Blanchard, Janice
Davey, Kevin
author_facet Pandiselvam, Sathishkumar
Jena, Narendra N.
Ghatak‐Roy, Aditi
Dreyer, Nicholas
Naik, Nehal
Blanchard, Janice
Davey, Kevin
author_sort Pandiselvam, Sathishkumar
collection PubMed
description OBJECTIVES: HIV, hepatitis B, and hepatitis C remain significant causes of morbidity and mortality in low resource settings. Emergency department (ED)‐based screening has proven effective in decreasing the spread of undiagnosed disease, although such programs are rare in low–middle income countries. METHODS: A prospective, cross sectional study of all adult patients presenting to the ED in a 600‐bed teaching hospital in Tamil Nadu, India. This study used an opt‐in strategy in which patients were offered testing at the end of their ED visit. Costs of testing were paid out of pocket by patients. Patients with known HIV, hepatitis B, or hepatitis C were excluded from the study. RESULTS: During the study period 26,465 patients presented to the ED, and 18,286 patients consented to participate (68.9%). Among the 18,286 patients tested, 174 were positive for either HIV (39, 0.21%), hepatitis C (52, 0.28%), or hepatitis B (83, 0.45%). Three patients tested positive for both HIV and hepatitis C, and 1 patient tested positive for both HIV and hepatitis B. A total of 69.2% of patients with HIV, 61.2% of patients with hepatitis B, and 83% of patients with hepatitis C presented for reasons unrelated to their underlying diagnosis. CONCLUSION: Although limited to only 1 hospital in southern India, this study represents the largest ED‐based screening program for HIV, hepatitis B, and hepatitis C ever conducted in India or any other low–middle income countries. The majority of patients presented for reasons unrelated to their underlying diagnosis. Future research is needed on implementation strategies, cost feasibility, and linkage to care.
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spelling pubmed-78192662021-01-29 Prevalence of undiagnosed HIV, hepatitis B, and hepatitis C among patients in an Indian emergency department Pandiselvam, Sathishkumar Jena, Narendra N. Ghatak‐Roy, Aditi Dreyer, Nicholas Naik, Nehal Blanchard, Janice Davey, Kevin J Am Coll Emerg Physicians Open Infectious Disease OBJECTIVES: HIV, hepatitis B, and hepatitis C remain significant causes of morbidity and mortality in low resource settings. Emergency department (ED)‐based screening has proven effective in decreasing the spread of undiagnosed disease, although such programs are rare in low–middle income countries. METHODS: A prospective, cross sectional study of all adult patients presenting to the ED in a 600‐bed teaching hospital in Tamil Nadu, India. This study used an opt‐in strategy in which patients were offered testing at the end of their ED visit. Costs of testing were paid out of pocket by patients. Patients with known HIV, hepatitis B, or hepatitis C were excluded from the study. RESULTS: During the study period 26,465 patients presented to the ED, and 18,286 patients consented to participate (68.9%). Among the 18,286 patients tested, 174 were positive for either HIV (39, 0.21%), hepatitis C (52, 0.28%), or hepatitis B (83, 0.45%). Three patients tested positive for both HIV and hepatitis C, and 1 patient tested positive for both HIV and hepatitis B. A total of 69.2% of patients with HIV, 61.2% of patients with hepatitis B, and 83% of patients with hepatitis C presented for reasons unrelated to their underlying diagnosis. CONCLUSION: Although limited to only 1 hospital in southern India, this study represents the largest ED‐based screening program for HIV, hepatitis B, and hepatitis C ever conducted in India or any other low–middle income countries. The majority of patients presented for reasons unrelated to their underlying diagnosis. Future research is needed on implementation strategies, cost feasibility, and linkage to care. John Wiley and Sons Inc. 2020-12-07 /pmc/articles/PMC7819266/ /pubmed/33521780 http://dx.doi.org/10.1002/emp2.12328 Text en © 2020 The Authors. JACEP Open published by Wiley Periodicals LLC on behalf of the American College of Emergency Physicians. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Infectious Disease
Pandiselvam, Sathishkumar
Jena, Narendra N.
Ghatak‐Roy, Aditi
Dreyer, Nicholas
Naik, Nehal
Blanchard, Janice
Davey, Kevin
Prevalence of undiagnosed HIV, hepatitis B, and hepatitis C among patients in an Indian emergency department
title Prevalence of undiagnosed HIV, hepatitis B, and hepatitis C among patients in an Indian emergency department
title_full Prevalence of undiagnosed HIV, hepatitis B, and hepatitis C among patients in an Indian emergency department
title_fullStr Prevalence of undiagnosed HIV, hepatitis B, and hepatitis C among patients in an Indian emergency department
title_full_unstemmed Prevalence of undiagnosed HIV, hepatitis B, and hepatitis C among patients in an Indian emergency department
title_short Prevalence of undiagnosed HIV, hepatitis B, and hepatitis C among patients in an Indian emergency department
title_sort prevalence of undiagnosed hiv, hepatitis b, and hepatitis c among patients in an indian emergency department
topic Infectious Disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819266/
https://www.ncbi.nlm.nih.gov/pubmed/33521780
http://dx.doi.org/10.1002/emp2.12328
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