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rpoB mutations conferring rifampicin-resistance affect growth, stress response and motility in Vibrio vulnificus

Rifampicin is a broad-spectrum antibiotic that binds to the bacterial RNA polymerase (RNAP), compromising DNA transcription. Rifampicin resistance is common in several microorganisms and it is typically caused by point mutations in the gene encoding the β subunit of RNA polymerase, rpoB. Different r...

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Detalles Bibliográficos
Autores principales: Cutugno, Laura, Mc Cafferty, Jennifer, Pané-Farré, Jan, O’Byrne, Conor, Boyd, Aoife
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819355/
https://www.ncbi.nlm.nih.gov/pubmed/33186092
http://dx.doi.org/10.1099/mic.0.000991