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rpoB mutations conferring rifampicin-resistance affect growth, stress response and motility in Vibrio vulnificus
Rifampicin is a broad-spectrum antibiotic that binds to the bacterial RNA polymerase (RNAP), compromising DNA transcription. Rifampicin resistance is common in several microorganisms and it is typically caused by point mutations in the gene encoding the β subunit of RNA polymerase, rpoB. Different r...
Autores principales: | Cutugno, Laura, Mc Cafferty, Jennifer, Pané-Farré, Jan, O’Byrne, Conor, Boyd, Aoife |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Microbiology Society
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819355/ https://www.ncbi.nlm.nih.gov/pubmed/33186092 http://dx.doi.org/10.1099/mic.0.000991 |
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