All‐trans retinoic acid induces leukemia resistance to NK cell cytotoxicity by down‐regulating B7‐H6 expression via c‐Myc signaling

BACKGROUND: The interaction between activating receptor NKp30 and its major tumor ligand B7‐H6 is important for NK cell‐mediated tumor rejection. However, the regulation of B7‐H6 by tumor therapeutics remains largely unknown. In this study, we investigated the regulation of B7‐H6 by all‐trans retino...

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Detalles Bibliográficos
Autores principales: Cao, Guoshuai, Cheng, Ying, Zheng, Xiaodong, Wei, Haiming, Tian, Zhigang, Sun, Rui, Sun, Haoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819554/
https://www.ncbi.nlm.nih.gov/pubmed/34236140
http://dx.doi.org/10.1002/cac2.12121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819554/
https://www.ncbi.nlm.nih.gov/pubmed/34236140
http://dx.doi.org/10.1002/cac2.12121

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