Depletion of protein kinase STK25 ameliorates renal lipotoxicity and protects against diabetic kidney disease

Diabetic kidney disease (DKD) is the most common cause of severe renal disease worldwide and the single strongest predictor of mortality in diabetes patients. Kidney steatosis has emerged as a critical trigger in the pathogenesis of DKD; however, the molecular mechanism of renal lipotoxicity remains...

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Detalles Bibliográficos
Autores principales: Cansby, Emmelie, Caputo, Mara, Gao, Lei, Kulkarni, Nagaraj M., Nerstedt, Annika, Ståhlman, Marcus, Borén, Jan, Porosk, Rando, Soomets, Ursel, Pedrelli, Matteo, Parini, Paolo, Marschall, Hanns-Ulrich, Nyström, Jenny, Howell, Brian W., Mahlapuu, Margit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819747/
https://www.ncbi.nlm.nih.gov/pubmed/33170807
http://dx.doi.org/10.1172/jci.insight.140483

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