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Rapid GMP-Compliant Expansion of SARS-CoV-2–Specific T Cells From Convalescent Donors for Use as an Allogeneic Cell Therapy for COVID-19
COVID-19 disease caused by the SARS-CoV-2 virus is characterized by dysregulation of effector T cells and accumulation of exhausted T cells. T cell responses to viruses can be corrected by adoptive cellular therapy using donor-derived virus-specific T cells. One approach is the establishment of bank...
Autores principales: | Cooper, Rachel S., Fraser, Alasdair R., Smith, Linda, Burgoyne, Paul, Imlach, Stuart N., Jarvis, Lisa M., Turner, David M., Zahra, Sharon, Turner, Marc L., Campbell, John D. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819874/ https://www.ncbi.nlm.nih.gov/pubmed/33488592 http://dx.doi.org/10.3389/fimmu.2020.598402 |
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