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Breed-related expression patterns of Ki67, γH2AX, and p21 during ageing in the canine liver

Cellular senescence is a molecular hallmark of ageing that is associated with multiple pathologies, and DNA damage marker γH2AX, together with cell cycle inhibitor p21, have been used as senescence markers in multiple species including dogs. Idiopathic canine chronic hepatitis has recognised breed-r...

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Detalles Bibliográficos
Autores principales: Hardwick, Laura J. A., Kortum, Andre J., Constantino-Casas, Fernando, Watson, Penny J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819948/
https://www.ncbi.nlm.nih.gov/pubmed/33301127
http://dx.doi.org/10.1007/s11259-020-09784-x