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Protocol for a mouse CNS demyelination model induced by a combination of HSV-1 and IL-2
Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system. Although viruses have been suggested to be a contributing environmental factor, conventional experimental MS mouse models do not account for this aspect. Here, we describe a mouse model to induce and evalua...
Autores principales: | Hirose, Satoshi, Tormanen, Kati, Kato, Mihoko, Yu, Jack, Ghiasi, Homayon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820129/ https://www.ncbi.nlm.nih.gov/pubmed/33521681 http://dx.doi.org/10.1016/j.xpro.2020.100287 |
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