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Protocol for a mouse CNS demyelination model induced by a combination of HSV-1 and IL-2

Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system. Although viruses have been suggested to be a contributing environmental factor, conventional experimental MS mouse models do not account for this aspect. Here, we describe a mouse model to induce and evalua...

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Detalles Bibliográficos
Autores principales: Hirose, Satoshi, Tormanen, Kati, Kato, Mihoko, Yu, Jack, Ghiasi, Homayon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820129/
https://www.ncbi.nlm.nih.gov/pubmed/33521681
http://dx.doi.org/10.1016/j.xpro.2020.100287

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