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Iron-rich Kupffer cells exhibit phenotypic changes during the development of liver fibrosis in NASH
Although recent evidence suggests the involvement of iron accumulation in the pathogenesis of nonalcoholic steatohepatitis (NASH), the underlying mechanisms remain poorly understood. Previously, we reported a unique histological structure termed “crown-like structure (CLS),” where liver-resident mac...
Autores principales: | Kanamori, Yohei, Tanaka, Miyako, Itoh, Michiko, Ochi, Kozue, Ito, Ayaka, Hidaka, Isao, Sakaida, Isao, Ogawa, Yoshihiro, Suganami, Takayoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820131/ https://www.ncbi.nlm.nih.gov/pubmed/33521599 http://dx.doi.org/10.1016/j.isci.2020.102032 |
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