Cargando…

Radiation-induced abscopal effect and its enhancement by programmed cell death 1 blockade in the hepatocellular carcinoma: A murine model study

BACKGROUND/AIMS: The abscopal effect, a rare phenomenon induced by radiation, can be reinforced by immunotherapy. Although radiation therapy and immunotherapy are increasingly being utilized for the treatment of hepatocellular carcinoma (HCC), whether immunotherapy could boost the abscopal effect re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yoo, Gyu Sang, Ahn, Won-Gyun, Kim, Shin-Yeong, Kang, Wonseok, Choi, Changhoon, Park, Hee Chul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Association for the Study of the Liver 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820196/ https://www.ncbi.nlm.nih.gov/pubmed/33280350 http://dx.doi.org/10.3350/cmh.2020.0095

Ejemplares similares

Antigen-Capturing Mesoporous Silica Nanoparticles Enhance the Radiation-Induced Abscopal Effect in Murine Hepatocellular Carcinoma Hepa1-6 Models
por: Yang, Kyungmi, et al.
Publicado: (2021)

Exploring the mythical abscopal effect: Radiation and programmed cell death protein 1 (PD-1) blockade for hepatocellular carcinoma
por: Kim, Jun Won, et al.
Publicado: (2021)

Optimizing radiotherapy with immune checkpoint blockade in hepatocellular carcinoma
por: Choi, Changhoon, et al.
Publicado: (2019)

Immune blockade inhibitors and the radiation abscopal effect in gastrointestinal cancers
por: Voutsadakis, Ioannis A
Publicado: (2018)

CD73 blockade enhances the local and abscopal effects of radiotherapy in a murine rectal cancer model
por: Tsukui, Hidenori, et al.
Publicado: (2020)

Radiation, Immune Checkpoint Blockade and the Abscopal Effect: A Critical Review on Timing, Dose and Fractionation
por: Buchwald, Zachary S., et al.
Publicado: (2018)

Topical Application of Phlorotannins from Brown Seaweed Mitigates Radiation Dermatitis in a Mouse Model
por: Yang, Kyungmi, et al.
Publicado: (2020)

The abscopal effect of local radiotherapy is induced by TGFβ blockade
por: Diamond, Julie, et al.
Publicado: (2013)

Abscopal effect of radiation on lung metastases of hepatocellular carcinoma: a case report
por: Okuma, Kae, et al.
Publicado: (2011)

Programmed cell death-1 blockade in combination with stereotactic radiation in an orthotopic mouse model of hepatocellular carcinoma
por: Friedman, David, et al.
Publicado: (2015)

Clinical significance of radiotherapy before and/or during nivolumab treatment in hepatocellular carcinoma
por: Yu, Jeong Il, et al.
Publicado: (2019)

Immunomodulation of HDAC Inhibitor Entinostat Potentiates the Anticancer Effects of Radiation and PD-1 Blockade in the Murine Lewis Lung Carcinoma Model
por: Kim, Yeeun, et al.
Publicado: (2022)

Systemic benefit of radiation therapy via abscopal effect
por: Craig, Daniel J., et al.
Publicado: (2022)

Radiotherapy-Mediated Immunomodulation and Anti-Tumor Abscopal Effect Combining Immune Checkpoint Blockade
por: Zhao, Xinrui, et al.
Publicado: (2020)

Radiotherapy in combination with CD47 blockade elicits a macrophage-mediated abscopal effect
por: Nishiga, Yoko, et al.
Publicado: (2022)

Downregulation of Mcl-1 by Panobinostat Potentiates Proton Beam Therapy in Hepatocellular Carcinoma Cells
por: Choi, Changhoon, et al.
Publicado: (2021)

Radiation therapy induces an abscopal effect and upregulates programmed death‐ligand 1 expression in a patient with non‐small cell lung cancer
por: Morita, Yutaka, et al.
Publicado: (2022)

Immune Modulation and Stereotactic Radiation: Improving Local and Abscopal Responses
por: Zeng, Jing, et al.
Publicado: (2013)

Abscopal effects of thoracic X-ray radiation on spermatogenesis in mice
por: Lai, Pan-Pan, et al.
Publicado: (2022)

Immunomodulatory effect of splenectomy in lung cancer mouse xenograft models receiving radiation therapy
por: Kim, Yeeun, et al.
Publicado: (2022)

Abscopal Effect, From Myth to Reality: From Radiation Oncologists' Perspective
por: Yilmaz, Melek Tugce, et al.
Publicado: (2019)

Abscopal Effect after Palliative Radiation Therapy for Metastatic Adenocarcinoma of the Esophagus
por: Bruton Joe, Moss, et al.
Publicado: (2018)

Radiation Therapy and its Effects Beyond the Primary Target: An Abscopal Effect
por: Wani, Shaqul Qamar, et al.
Publicado: (2019)

Abscopal effect of radiation in metastatic esophageal carcinoma: fourth reported case
por: Biswas, Rituparna, et al.
Publicado: (2023)

Influence of low-dose radiation on abscopal responses in patients receiving high-dose radiation and immunotherapy
por: Menon, Hari, et al.
Publicado: (2019)

Clinical importance of the absolute count of neutrophils, lymphocytes, monocytes, and platelets in newly diagnosed hepatocellular carcinoma
por: Yu, Jeong Il, et al.
Publicado: (2021)

Abscopal effect in pulmonary carcinoid tumor following ablative stereotactic body radiation therapy: a case report
por: Kareff, Samuel A., et al.
Publicado: (2020)

Bone marrow stem cell dysfunction in radiation-induced abscopal bone loss
por: Zou, Qiong, et al.
Publicado: (2016)

Radiation-induced bystander and abscopal effects: important lessons from preclinical models
por: Daguenet, Elisabeth, et al.
Publicado: (2020)

Radiation Therapy as a Modality to Create Abscopal Effects: Current and Future Practices
por: Adjepong, Dennis, et al.
Publicado: (2020)

Trends in the Abscopal Effect After Radiation to Spinal Metastases: A Systematic Review
por: Macki, Mohamed, et al.
Publicado: (2019)

Radiation Induced Abscopal Effect in a Patient With Malignant Pleural Mesothelioma on Pembrolizumab
por: Rittberg, Rebekah, et al.
Publicado: (2022)

Immunocytokine augments local and abscopal response and animal survival when added to radiation and CTLA-4 checkpoint inhibition in a murine melanoma model
por: Morris, Zachary S, et al.
Publicado: (2015)

Abscopal effect in the radio and immunotherapy
por: Pevzner, Alina M., et al.
Publicado: (2021)

Targeting the inhibitory receptor CTLA-4 on T cells increased abscopal effects in murine mesothelioma model
por: Wu, Licun, et al.
Publicado: (2015)

Metformin combined with local irradiation provokes abscopal effects in a murine rectal cancer model
por: Tojo, Mineyuki, et al.
Publicado: (2022)

In-field and abscopal response after short-course radiation therapy in patients with metastatic Merkel cell carcinoma progressing on PD-1 checkpoint blockade: a case series
por: Xu, Melody J., et al.
Publicado: (2018)

Comparison of Proton and Photon Beam Irradiation in Radiation-Induced Intestinal Injury Using a Mouse Model
por: Choi, Changhoon, et al.
Publicado: (2019)

Diffusion-weighted and dynamic contrast-enhanced magnetic resonance imaging after radiation therapy for bone metastases in patients with hepatocellular carcinoma
por: Lee, Ji Hyun, et al.
Publicado: (2021)

The Abscopal Effect of Radiation Therapy: What Is It and How Can We Use It in Breast Cancer?
por: Hu, Zishuo I., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_pmllvisd2dii00qob2ntsh1kc1