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A nuclear protein, PfMORC confers melatonin dependent synchrony of the human malaria parasite P. falciparum in the asexual stage
The host hormone melatonin is known to modulate the asexual cell-cycle of the human malaria parasite Plasmodium falciparum and the kinase PfPK7 is fundamental in the downstream signaling pathways. The nuclear protein PfMORC displays a histidine kinase domain and is involved in parasite cell cycle co...
Autores principales: | Singh, Maneesh K., Tessarin-Almeida, Giulliana, Dias, Barbara K. M., Pereira, Pedro Scarpellli, Costa, Fahyme, Przyborski, Jude M., Garcia, Celia R. S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820235/ https://www.ncbi.nlm.nih.gov/pubmed/33479315 http://dx.doi.org/10.1038/s41598-021-81235-2 |
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