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Serum naturally occurring anti-TDP-43 auto-antibodies are increased in amyotrophic lateral sclerosis

Amyotrophic Lateral Sclerosis (ALS) patients express significant clinical heterogeneity that often hinders a correct diagnostic definition. Intracellular deposition of TDP-43, a protein involved in RNA metabolism characterizes the pathology. Interestingly, this protein can be detected in serum, wher...

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Detalles Bibliográficos
Autores principales:	Conti, Elisa, Sala, Gessica, Diamanti, Susanna, Casati, Marco, Lunetta, Christian, Gerardi, Francesca, Tarlarini, Claudia, Mosca, Lorena, Riva, Nilo, Falzone, Yuri, Filippi, Massimo, Appollonio, Ildebrando, Ferrarese, Carlo, Tremolizzo, Lucio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820419/ https://www.ncbi.nlm.nih.gov/pubmed/33479441 http://dx.doi.org/10.1038/s41598-021-81599-5

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