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Role of osteogenic Dickkopf-1 in bone remodeling and bone healing in mice with type I diabetes mellitus
Type 1 diabetes mellitus (T1DM) is associated with low bone mass and a higher risk for fractures. Dickkopf-1 (Dkk1), which inhibits Wnt signaling, osteoblast function, and bone formation, has been found to be increased in the serum of patients with T1DM. Here, we investigated the functional role of...
Autores principales: | Hildebrandt, Nick, Colditz, Juliane, Dutra, Caio, Goes, Paula, Salbach-Hirsch, Juliane, Thiele, Sylvia, Hofbauer, Lorenz C., Rauner, Martina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820472/ https://www.ncbi.nlm.nih.gov/pubmed/33479403 http://dx.doi.org/10.1038/s41598-021-81543-7 |
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