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Repeat DNA-PAINT suppresses background and non-specific signals in optical nanoscopy
DNA-PAINT is a versatile optical super-resolution technique relying on the transient binding of fluorescent DNA ‘imagers’ to target epitopes. Its performance in biological samples is often constrained by strong background signals and non-specific binding events, both exacerbated by high imager conce...
Autores principales: | Clowsley, Alexander H., Kaufhold, William T., Lutz, Tobias, Meletiou, Anna, Di Michele, Lorenzo, Soeller, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820506/ https://www.ncbi.nlm.nih.gov/pubmed/33479249 http://dx.doi.org/10.1038/s41467-020-20686-z |
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