GATA2 regulates mast cell identity and responsiveness to antigenic stimulation by promoting chromatin remodeling at super-enhancers

Mast cells are critical effectors of allergic inflammation and protection against parasitic infections. We previously demonstrated that transcription factors GATA2 and MITF are the mast cell lineage-determining factors. However, it is unclear whether these lineage-determining factors regulate chroma...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yapeng, Gao, Junfeng, Kamran, Mohammad, Harmacek, Laura, Danhorn, Thomas, Leach, Sonia M., O’Connor, Brian P., Hagman, James R., Huang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820599/
https://www.ncbi.nlm.nih.gov/pubmed/33479210
http://dx.doi.org/10.1038/s41467-020-20766-0

Ejemplares similares

Ejemplares similares