Cargando…

Protective Role of the Nucleic Acid Sensor STING in Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is the most common and severe type of interstitial lung disease for which current treatments display limited efficacy. IPF is largely driven by host-derived danger signals released upon recurrent local tissue damage. Here we explored the roles of self-DNA and stim...

Descripción completa

Detalles Bibliográficos
Autores principales:	Savigny, Florence, Schricke, Corinne, Lacerda-Queiroz, Norinne, Meda, Mélanie, Nascimento, Mégane, Huot-Marchand, Sarah, Da Gama Monteiro, Felipe, Ryffel, Bernhard, Gombault, Aurélie, Le Bert, Marc, Couillin, Isabelle, Riteau, Nicolas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820752/ https://www.ncbi.nlm.nih.gov/pubmed/33488589 http://dx.doi.org/10.3389/fimmu.2020.588799

Ejemplares similares

Self-DNA release and STING-dependent sensing drives inflammation to cigarette smoke in mice
por: Nascimento, Mégane, et al.
Publicado: (2019)

B-Cell Activating Factor Secreted by Neutrophils Is a Critical Player in Lung Inflammation to Cigarette Smoke Exposure
por: Nascimento, Mégane, et al.
Publicado: (2020)

Cigarette smoke-induced gasdermin D activation in bronchoalveolar macrophages and bronchial epithelial cells dependently on NLRP3
por: Huot-Marchand, Sarah, et al.
Publicado: (2022)

STING Targeting in Lung Diseases
por: de Moura Rodrigues, Dorian, et al.
Publicado: (2022)

The IL-33 Receptor ST2 Regulates Pulmonary Inflammation and Fibrosis to Bleomycin
por: Fanny, Manoussa, et al.
Publicado: (2018)

Lung inflammation and interstitial fibrosis by targeted alveolar epithelial type I cell death
por: Carignon, Sandra, et al.
Publicado: (2023)

ATP release and purinergic signaling: a common pathway for particle-mediated inflammasome activation
por: Riteau, N, et al.
Publicado: (2012)

STING Signaling and Sterile Inflammation
por: Couillin, Isabelle, et al.
Publicado: (2021)

The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosine
por: Baron, L, et al.
Publicado: (2015)

ATP release and purinergic signaling in NLRP3 inflammasome activation
por: Gombault, Aurélie, et al.
Publicado: (2013)

Discordance in cathepsin B and cystatin C expressions in bronchoalveolar fluids between murine bleomycin-induced fibrosis and human idiopathic fibrosis
por: Kasabova, Mariana, et al.
Publicado: (2016)

Mechanism of splenic cell death and host mortality in a Plasmodium yoelii malaria model
por: Lacerda-Queiroz, Norinne, et al.
Publicado: (2017)

IL-1 and IL-23 Mediate Early IL-17A Production in Pulmonary Inflammation Leading to Late Fibrosis
por: Gasse, Paméla, et al.
Publicado: (2011)

Severity of Scorpion Stings in the Western Brazilian Amazon: A Case-Control Study
por: Queiroz, Amanda M., et al.
Publicado: (2015)

STING agonist diABZI induces PANoptosis and DNA mediated acute respiratory distress syndrome (ARDS)
por: Messaoud-Nacer, Yasmine, et al.
Publicado: (2022)

Splitting aptamers and nucleic acid enzymes for the development of advanced biosensors
por: Debiais, Mégane, et al.
Publicado: (2020)

Natterin-Induced Neutrophilia Is Dependent on cGAS/STING Activation via Type I IFN Signaling Pathway
por: Lima, Carla, et al.
Publicado: (2022)

Interleukin-17 is a negative regulator of established allergic asthma
por: Schnyder-Candrian, Silvia, et al.
Publicado: (2006)

Molecular basis of carrageenan-induced cytokines production in macrophages
por: Lopes, Alexandre H., et al.
Publicado: (2020)

Blockade of IL-33R/ST2 Signaling Attenuates Toxoplasma gondii Ileitis Depending on IL-22 Expression
por: Ryffel, Bernhard, et al.
Publicado: (2019)

Corrigendum: Blockade of IL-33R/ST2 Signaling Attenuates Toxoplasma gondii Ileitis Depending on IL-22 Expression
por: Ryffel, Bernhard, et al.
Publicado: (2020)

STING-dependent sensing of self-DNA drives silica-induced lung inflammation
por: Benmerzoug, Sulayman, et al.
Publicado: (2018)

Phosphatidylinositol 3-Kinase γ Is Required for the Development of Experimental Cerebral Malaria
por: Lacerda-Queiroz, Norinne, et al.
Publicado: (2015)

A novel transcript isoform of STING that sequesters cGAMP and dominantly inhibits innate nucleic acid sensing
por: Wang, Pei-Hui, et al.
Publicado: (2018)

P2X7 Receptor Promotes Mouse Mammary Cancer Cell Invasiveness and Tumour Progression, and Is a Target for Anticancer Treatment
por: Brisson, Lucie, et al.
Publicado: (2020)

Sting /
por: Leduc, Jean-Marie
Publicado: (1992)

Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing
por: Kessler, Nina, et al.
Publicado: (2022)

Nucleic acid sensor STING drives remodeling and its inhibition enhances steroid responsiveness in chronic obstructive pulmonary disease
por: Mdkhana, Bushra, et al.
Publicado: (2023)

CD4 T cell-intrinsic STING signaling controls the differentiation and effector functions of T(H)1 and T(H)9 cells
por: Benoit-Lizon, Isis, et al.
Publicado: (2022)

Uncoupling between Inflammatory and Fibrotic Responses to Silica: Evidence from MyD88 Knockout Mice
por: Lo Re, Sandra, et al.
Publicado: (2014)

Human Cancer Cells Sense Cytosolic Nucleic Acids Through the RIG-I–MAVS Pathway and cGAS–STING Pathway
por: Qiao, Yuan, et al.
Publicado: (2021)

Correction: Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing
por: Kessler, Nina, et al.
Publicado: (2022)

STING is an intrinsic checkpoint inhibitor that restrains the T(H)17 cell pathogenic program
por: Damasceno, Luis Eduardo Alves, et al.
Publicado: (2022)

Impact of STING Inflammatory Signaling during Intracellular Bacterial Infections
por: Guimarães, Erika S., et al.
Publicado: (2021)

The Buzz and the Sting
por: Bahabri, Sultan Abdullah
Publicado: (2002)

Hornet Sting
por: Finlayson, Walter J.
Publicado: (1908)

Insect Stings
Publicado: (1890)

Case of Sting
por: Lundy, E. L.
Publicado: (1876)

Wasp Sting
por: Watson, John
Publicado: (1905)

Bee Stings
Publicado: (1871)

Cannot write session to /tmp/vufind_sessions/sess_k1hba21o9r3h96prv68mttl9tc