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Exponential Damping: The Key to Successful Containment of COVID-19
Due to its excessive capacity for human-to-human transmission, the 2019 coronavirus disease (COVID-19) has now been declared a global public health emergency. Here we propose a simple model based on exponential infectious growth, but with a time-varying, largely damping, transmission rate. This mode...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820870/ https://www.ncbi.nlm.nih.gov/pubmed/33490016 http://dx.doi.org/10.3389/fpubh.2020.580619 |
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author | Zhang, Feng Zhang, Jinmei Cao, Menglan Zhang, Yong Hui, Cang |
author_facet | Zhang, Feng Zhang, Jinmei Cao, Menglan Zhang, Yong Hui, Cang |
author_sort | Zhang, Feng |
collection | PubMed |
description | Due to its excessive capacity for human-to-human transmission, the 2019 coronavirus disease (COVID-19) has now been declared a global public health emergency. Here we propose a simple model based on exponential infectious growth, but with a time-varying, largely damping, transmission rate. This model provides an excellent fit to the existing data for 46 countries with 10,000+ cases by 16 May 2020, five continents and the entire world. Hence, the model has largely captured the transmission patterns of the COVID-19 outbreak under a variety of intervention and control measures. The damping rate ranged from −0.0228 to 0.1669 d(−1) globally (a negative damping rate represents acceleration in spread) and can greatly affect the duration of the outbreak and the eventual number of infections. Our model suggests that it is possible to defeat the COVID-19 pandemic by the end of 2020 through achieving a high damping rate (0.0615 d(−1)). However, the global damping rate is rather low (0.0504 d(−1) before 26 April) and has dropped even further since late April (0.0168 d(−1)). Easing currently implemented control measures in countries with weak or no damping in transmission could lead to an exponential rebound of COVID-19 spread. |
format | Online Article Text |
id | pubmed-7820870 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-78208702021-01-23 Exponential Damping: The Key to Successful Containment of COVID-19 Zhang, Feng Zhang, Jinmei Cao, Menglan Zhang, Yong Hui, Cang Front Public Health Public Health Due to its excessive capacity for human-to-human transmission, the 2019 coronavirus disease (COVID-19) has now been declared a global public health emergency. Here we propose a simple model based on exponential infectious growth, but with a time-varying, largely damping, transmission rate. This model provides an excellent fit to the existing data for 46 countries with 10,000+ cases by 16 May 2020, five continents and the entire world. Hence, the model has largely captured the transmission patterns of the COVID-19 outbreak under a variety of intervention and control measures. The damping rate ranged from −0.0228 to 0.1669 d(−1) globally (a negative damping rate represents acceleration in spread) and can greatly affect the duration of the outbreak and the eventual number of infections. Our model suggests that it is possible to defeat the COVID-19 pandemic by the end of 2020 through achieving a high damping rate (0.0615 d(−1)). However, the global damping rate is rather low (0.0504 d(−1) before 26 April) and has dropped even further since late April (0.0168 d(−1)). Easing currently implemented control measures in countries with weak or no damping in transmission could lead to an exponential rebound of COVID-19 spread. Frontiers Media S.A. 2021-01-08 /pmc/articles/PMC7820870/ /pubmed/33490016 http://dx.doi.org/10.3389/fpubh.2020.580619 Text en Copyright © 2021 Zhang, Zhang, Cao, Zhang and Hui. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Public Health Zhang, Feng Zhang, Jinmei Cao, Menglan Zhang, Yong Hui, Cang Exponential Damping: The Key to Successful Containment of COVID-19 |
title | Exponential Damping: The Key to Successful Containment of COVID-19 |
title_full | Exponential Damping: The Key to Successful Containment of COVID-19 |
title_fullStr | Exponential Damping: The Key to Successful Containment of COVID-19 |
title_full_unstemmed | Exponential Damping: The Key to Successful Containment of COVID-19 |
title_short | Exponential Damping: The Key to Successful Containment of COVID-19 |
title_sort | exponential damping: the key to successful containment of covid-19 |
topic | Public Health |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820870/ https://www.ncbi.nlm.nih.gov/pubmed/33490016 http://dx.doi.org/10.3389/fpubh.2020.580619 |
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