Cortical inexcitability defines an adverse clinical profile in amyotrophic lateral sclerosis

BACKGROUND AND PURPOSE: In amyotrophic lateral sclerosis, studies using threshold‐tracking transcranial magnetic stimulation (TMS) have identified corticomotoneuronal dysfunction as a key pathogenic mechanism. Some patients, however, display no motor response at maximal TMS intensities, termed here...

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Detalles Bibliográficos
Autores principales: Dharmadasa, T., Howells, J., Matamala, J. M., Simon, N. G., Burke, D., Vucic, S., Kiernan, M. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
ALS and frontotemporal dementia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820947/
https://www.ncbi.nlm.nih.gov/pubmed/32902860
http://dx.doi.org/10.1111/ene.14515

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