Long‐term survival of participants in the CENTAUR trial of sodium phenylbutyrate‐taurursodiol in amyotrophic lateral sclerosis

An orally administered, fixed‐dose coformulation of sodium phenylbutyrate‐taurursodiol (PB‐TURSO) significantly slowed functional decline in a randomized, placebo‐controlled, phase 2 trial in ALS (CENTAUR). Herein we report results of a long‐term survival analysis of participants in CENTAUR. In CENT...

Descripción completa

Detalles Bibliográficos
Autores principales: Paganoni, Sabrina, Hendrix, Suzanne, Dickson, Samuel P., Knowlton, Newman, Macklin, Eric A., Berry, James D., Elliott, Michael A., Maiser, Samuel, Karam, Chafic, Caress, James B., Owegi, Margaret Ayo, Quick, Adam, Wymer, James, Goutman, Stephen A., Heitzman, Daragh, Heiman‐Patterson, Terry D., Jackson, Carlayne E., Quinn, Colin, Rothstein, Jeffrey D., Kasarskis, Edward J., Katz, Jonathan, Jenkins, Liberty, Ladha, Shafeeq, Miller, Timothy M., Scelsa, Stephen N., Vu, Tuan H., Fournier, Christina N., Glass, Jonathan D., Johnson, Kristin M., Swenson, Andrea, Goyal, Namita A., Pattee, Gary L., Andres, Patricia L., Babu, Suma, Chase, Marianne, Dagostino, Derek, Hall, Meghan, Kittle, Gale, Eydinov, Matthew, McGovern, Michelle, Ostrow, Joseph, Pothier, Lindsay, Randall, Rebecca, Shefner, Jeremy M., Sherman, Alexander V., St Pierre, Maria E., Tustison, Eric, Vigneswaran, Prasha, Walker, Jason, Yu, Hong, Chan, James, Wittes, Janet, Yu, Zi‐Fan, Cohen, Joshua, Klee, Justin, Leslie, Kent, Tanzi, Rudolph E., Gilbert, Walter, Yeramian, Patrick D., Schoenfeld, David, Cudkowicz, Merit E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Clinical Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820979/
https://www.ncbi.nlm.nih.gov/pubmed/33063909
http://dx.doi.org/10.1002/mus.27091

Ejemplares similares

Ejemplares similares