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CPT2 down-regulation promotes tumor growth and metastasis through inducing ROS/NFκB pathway in ovarian cancer

BACKGROUND: Carnitine palmitoyltransferase 2 (CPT2) is a rate-limiting enzyme involved in fatty acid β-oxidation (FAO) regulation. Recently, it has been increasingly recognized that lipid metabolism dysregulation is closely implicated in tumorigenesis. However, the involvement of CPT2 in the progres...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaohong, Zhang, Zhen, Liu, Shujuan, Li, Jia, Wu, Liying, Lv, Xiaohui, Xu, Jia, Chen, Biliang, Zhao, Shuhua, Yang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821038/
https://www.ncbi.nlm.nih.gov/pubmed/33486313
http://dx.doi.org/10.1016/j.tranon.2021.101023