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CPT2 down-regulation promotes tumor growth and metastasis through inducing ROS/NFκB pathway in ovarian cancer
BACKGROUND: Carnitine palmitoyltransferase 2 (CPT2) is a rate-limiting enzyme involved in fatty acid β-oxidation (FAO) regulation. Recently, it has been increasingly recognized that lipid metabolism dysregulation is closely implicated in tumorigenesis. However, the involvement of CPT2 in the progres...
Autores principales: | Zhang, Xiaohong, Zhang, Zhen, Liu, Shujuan, Li, Jia, Wu, Liying, Lv, Xiaohui, Xu, Jia, Chen, Biliang, Zhao, Shuhua, Yang, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821038/ https://www.ncbi.nlm.nih.gov/pubmed/33486313 http://dx.doi.org/10.1016/j.tranon.2021.101023 |
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