Cargando…

Evaluation of TH-Cre knock-in cell lines for detection and specific targeting of stem cell-derived dopaminergic neurons

The focal and progressive degeneration of dopaminergic (DA) neurons in ventral midbrain has made Parkinson's disease (PD) a particularly interesting target of cell-based therapies. However, ethical issues and limited tissue availability have so far hindered the widespread use of human fetal tis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fiorenzano, Alessandro, Birtele, Marcella, Wahlestedt, Jenny Nelander, Parmar, Malin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821040/ https://www.ncbi.nlm.nih.gov/pubmed/33532642 http://dx.doi.org/10.1016/j.heliyon.2021.e06006

Ejemplares similares

Single-cell transcriptional and functional analysis of dopaminergic neurons in organoid-like cultures derived from human fetal midbrain
por: Birtele, Marcella, et al.
Publicado: (2022)

Single-Cell Profiling of Coding and Noncoding Genes in Human Dopamine Neuron Differentiation
por: Nilsson, Fredrik, et al.
Publicado: (2021)

Direct Reprogramming of Human Fetal- and Stem Cell-Derived Glial Progenitor Cells into Midbrain Dopaminergic Neurons
por: Nolbrant, Sara, et al.
Publicado: (2020)

Dopamine Neuron Diversity: Recent Advances and Current Challenges in Human Stem Cell Models and Single Cell Sequencing
por: Fiorenzano, Alessandro, et al.
Publicado: (2021)

Impact of α-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized α-synuclein rat model of PD
por: Hoban, Deirdre B., et al.
Publicado: (2020)

Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organoids
por: Fiorenzano, Alessandro, et al.
Publicado: (2021)

Author Correction: Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organoids
por: Fiorenzano, Alessandro, et al.
Publicado: (2022)

Generating regionalized neuronal cells from pluripotency, a step-by-step protocol
por: Kirkeby, Agnete, et al.
Publicado: (2013)

hESC-Derived Dopaminergic Transplants Integrate into Basal Ganglia Circuitry in a Preclinical Model of Parkinson’s Disease
por: Adler, Andrew F., et al.
Publicado: (2019)

Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease
por: Tiklová, Katarína, et al.
Publicado: (2020)

A glycine transporter 2-Cre knock-in mouse line for glycinergic neuron-specific gene manipulation
por: Kakizaki, Toshikazu, et al.
Publicado: (2017)

Author Correction: Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease
por: Tiklová, Katarína, et al.
Publicado: (2020)

Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor
por: Jönsson, Marie E., et al.
Publicado: (2015)

Tg(Th-Cre)FI172Gsat (Th-Cre) defines neurons that are required for full hypercapnic and hypoxic reflexes
por: Sun, Jenny J., et al.
Publicado: (2017)

Silk scaffolding drives self-assembly of functional and mature human brain organoids
por: Sozzi, Edoardo, et al.
Publicado: (2022)

Age-related pathological impairments in directly reprogrammed dopaminergic neurons derived from patients with idiopathic Parkinson’s disease
por: Drouin-Ouellet, Janelle, et al.
Publicado: (2022)

Target‐specific forebrain projections and appropriate synaptic inputs of hESC‐derived dopamine neurons grafted to the midbrain of parkinsonian rats
por: Cardoso, Tiago, et al.
Publicado: (2018)

Toxic and Phenotypic Effects of AAV_Cre Used to Transduce Mesencephalic Dopaminergic Neurons
por: Erben, Larissa, et al.
Publicado: (2022)

Generation of an Rx-tTA: TetOp-Cre Knock-In Mouse Line for Doxycycline Regulated Cre Activity in the Rx Expression Domain
por: Plageman, Timothy F., et al.
Publicado: (2012)

Direct Reprogramming of Resident NG2 Glia into Neurons with Properties of Fast-Spiking Parvalbumin-Containing Interneurons
por: Pereira, Maria, et al.
Publicado: (2017)

Ins1(Cre) knock-in mice for beta cell-specific gene recombination
por: Thorens, Bernard, et al.
Publicado: (2014)

An Atoh1 CRE Knock-In Mouse Labels Motor Neurons Involved in Fine Motor Control
por: Ogujiofor, Osita W., et al.
Publicado: (2021)

Early specification of dopaminergic phenotype during ES cell differentiation
por: Parmar, Malin, et al.
Publicado: (2007)

Is LysM-Cre a good candidate Cre for knocking out Atg5 gene in mice?
por: Wen, Jun-Hao, et al.
Publicado: (2022)

Knock-In Rat Lines with Cre Recombinase at the Dopamine D1 and Adenosine 2a Receptor Loci
por: Pettibone, Jeffrey R., et al.
Publicado: (2019)

Targeting Morphine-Responsive Neurons: Generation of a Knock-In Mouse Line Expressing Cre Recombinase from the Mu-Opioid Receptor Gene Locus
por: Bailly, Julie, et al.
Publicado: (2020)

Validation of a Novel Fgf10(Cre–ERT2) Knock-in Mouse Line Targeting FGF10(Pos) Cells Postnatally
por: Chu, Xuran, et al.
Publicado: (2021)

Neuroanatomical characterization of the Nmu-Cre knock-in mice reveals an interconnected network of unique neuropeptidergic cells
por: Medrano, Mireia, et al.
Publicado: (2023)

Testing the Cre-mediated genetic switch for the generation of conditional knock-in mice
por: Capulli, Mattia, et al.
Publicado: (2019)

Differentiation of rhesus adipose stem cells into dopaminergic neurons☆
por: Zhou, Yan, et al.
Publicado: (2012)

Generation and Characterisation of a Pax8-CreER(T2) Transgenic Line and a Slc22a6-CreER(T2) Knock-In Line for Inducible and Specific Genetic Manipulation of Renal Tubular Epithelial Cells
por: Espana-Agusti, Judit, et al.
Publicado: (2016)

Isolation of Human Induced Pluripotent Stem Cell-Derived Dopaminergic Progenitors by Cell Sorting for Successful Transplantation
por: Doi, Daisuke, et al.
Publicado: (2014)

Automated microfluidic cell culture of stem cell derived dopaminergic neurons
por: Kane, Khalid I. W., et al.
Publicado: (2019)

Differentiation of adult human mesenchymal stem cells into dopaminergic neurons
por: Khademizadeh, Marjan, et al.
Publicado: (2019)

The Atoh1-Cre Knock-In Allele Ectopically Labels a Subpopulation of Amacrine Cells and Bipolar Cells in Mouse Retina
por: Wu, Sih-Rong, et al.
Publicado: (2023)

Application of CRISPR/Cas9 editing and digital droplet PCR in human iPSCs to generate novel knock-in reporter lines to visualize dopaminergic neurons
por: Überbacher, Christa, et al.
Publicado: (2019)

Characterisation of lamina I anterolateral system neurons that express Cre in a Phox2a-Cre mouse line
por: Alsulaiman, Wafa A. A., et al.
Publicado: (2021)

High-efficiency Rosa26 knock-in vector construction for Cre-regulated overexpression and RNAi
por: Hohenstein, Peter, et al.
Publicado: (2008)

Midbrain Dopaminergic Neuron Development at the Single Cell Level: In vivo and in Stem Cells
por: Ásgrímsdóttir, Emilía Sif, et al.
Publicado: (2020)

Midbrain dopaminergic neuron fate specification: Of mice and embryonic stem cells
por: Gale, Emily, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_69qs8rfblr9t81a64agdhvr6nc