Cargando…
Serial Interval and Generation Interval for Imported and Local Infectors, Respectively, Estimated Using Reported Contact-Tracing Data of COVID-19 in China
The emerging virus, COVID-19, has caused a massive outbreak worldwide. Based on the publicly available contact-tracing data, we identified 509 transmission chains from 20 provinces in China and estimated the serial interval (SI) and generation interval (GI) of COVID-19 in China. Inspired by differen...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821042/ https://www.ncbi.nlm.nih.gov/pubmed/33490015 http://dx.doi.org/10.3389/fpubh.2020.577431 |
_version_ | 1783639340641943552 |
---|---|
author | Li, Menghui Liu, Kai Song, Yukun Wang, Ming Wu, Jinshan |
author_facet | Li, Menghui Liu, Kai Song, Yukun Wang, Ming Wu, Jinshan |
author_sort | Li, Menghui |
collection | PubMed |
description | The emerging virus, COVID-19, has caused a massive outbreak worldwide. Based on the publicly available contact-tracing data, we identified 509 transmission chains from 20 provinces in China and estimated the serial interval (SI) and generation interval (GI) of COVID-19 in China. Inspired by different possible values of the time-varying reproduction number for the imported cases and the local cases in China, we divided all transmission events into three subsets: imported (the zeroth generation) infecting 1st-generation locals, 1st-generation locals infecting 2nd-generation locals, and other transmissions among 2+. The corresponding SI (GI) is respectively denoted as [Formula: see text] ([Formula: see text]), [Formula: see text] ([Formula: see text]), and [Formula: see text] ([Formula: see text]). A Bayesian approach with doubly interval-censored likelihood is employed to fit the distribution function of the SI and GI. It was found that the estimated [Formula: see text] , [Formula: see text] , [Formula: see text] , and [Formula: see text] , [Formula: see text] , [Formula: see text]. Thus, overall both SI and GI decrease when generation increases. |
format | Online Article Text |
id | pubmed-7821042 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-78210422021-01-23 Serial Interval and Generation Interval for Imported and Local Infectors, Respectively, Estimated Using Reported Contact-Tracing Data of COVID-19 in China Li, Menghui Liu, Kai Song, Yukun Wang, Ming Wu, Jinshan Front Public Health Public Health The emerging virus, COVID-19, has caused a massive outbreak worldwide. Based on the publicly available contact-tracing data, we identified 509 transmission chains from 20 provinces in China and estimated the serial interval (SI) and generation interval (GI) of COVID-19 in China. Inspired by different possible values of the time-varying reproduction number for the imported cases and the local cases in China, we divided all transmission events into three subsets: imported (the zeroth generation) infecting 1st-generation locals, 1st-generation locals infecting 2nd-generation locals, and other transmissions among 2+. The corresponding SI (GI) is respectively denoted as [Formula: see text] ([Formula: see text]), [Formula: see text] ([Formula: see text]), and [Formula: see text] ([Formula: see text]). A Bayesian approach with doubly interval-censored likelihood is employed to fit the distribution function of the SI and GI. It was found that the estimated [Formula: see text] , [Formula: see text] , [Formula: see text] , and [Formula: see text] , [Formula: see text] , [Formula: see text]. Thus, overall both SI and GI decrease when generation increases. Frontiers Media S.A. 2021-01-08 /pmc/articles/PMC7821042/ /pubmed/33490015 http://dx.doi.org/10.3389/fpubh.2020.577431 Text en Copyright © 2021 Li, Liu, Song, Wang and Wu. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Public Health Li, Menghui Liu, Kai Song, Yukun Wang, Ming Wu, Jinshan Serial Interval and Generation Interval for Imported and Local Infectors, Respectively, Estimated Using Reported Contact-Tracing Data of COVID-19 in China |
title | Serial Interval and Generation Interval for Imported and Local Infectors, Respectively, Estimated Using Reported Contact-Tracing Data of COVID-19 in China |
title_full | Serial Interval and Generation Interval for Imported and Local Infectors, Respectively, Estimated Using Reported Contact-Tracing Data of COVID-19 in China |
title_fullStr | Serial Interval and Generation Interval for Imported and Local Infectors, Respectively, Estimated Using Reported Contact-Tracing Data of COVID-19 in China |
title_full_unstemmed | Serial Interval and Generation Interval for Imported and Local Infectors, Respectively, Estimated Using Reported Contact-Tracing Data of COVID-19 in China |
title_short | Serial Interval and Generation Interval for Imported and Local Infectors, Respectively, Estimated Using Reported Contact-Tracing Data of COVID-19 in China |
title_sort | serial interval and generation interval for imported and local infectors, respectively, estimated using reported contact-tracing data of covid-19 in china |
topic | Public Health |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821042/ https://www.ncbi.nlm.nih.gov/pubmed/33490015 http://dx.doi.org/10.3389/fpubh.2020.577431 |
work_keys_str_mv | AT limenghui serialintervalandgenerationintervalforimportedandlocalinfectorsrespectivelyestimatedusingreportedcontacttracingdataofcovid19inchina AT liukai serialintervalandgenerationintervalforimportedandlocalinfectorsrespectivelyestimatedusingreportedcontacttracingdataofcovid19inchina AT songyukun serialintervalandgenerationintervalforimportedandlocalinfectorsrespectivelyestimatedusingreportedcontacttracingdataofcovid19inchina AT wangming serialintervalandgenerationintervalforimportedandlocalinfectorsrespectivelyestimatedusingreportedcontacttracingdataofcovid19inchina AT wujinshan serialintervalandgenerationintervalforimportedandlocalinfectorsrespectivelyestimatedusingreportedcontacttracingdataofcovid19inchina |