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Serial Interval and Generation Interval for Imported and Local Infectors, Respectively, Estimated Using Reported Contact-Tracing Data of COVID-19 in China

The emerging virus, COVID-19, has caused a massive outbreak worldwide. Based on the publicly available contact-tracing data, we identified 509 transmission chains from 20 provinces in China and estimated the serial interval (SI) and generation interval (GI) of COVID-19 in China. Inspired by differen...

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Autores principales: Li, Menghui, Liu, Kai, Song, Yukun, Wang, Ming, Wu, Jinshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821042/
https://www.ncbi.nlm.nih.gov/pubmed/33490015
http://dx.doi.org/10.3389/fpubh.2020.577431
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author Li, Menghui
Liu, Kai
Song, Yukun
Wang, Ming
Wu, Jinshan
author_facet Li, Menghui
Liu, Kai
Song, Yukun
Wang, Ming
Wu, Jinshan
author_sort Li, Menghui
collection PubMed
description The emerging virus, COVID-19, has caused a massive outbreak worldwide. Based on the publicly available contact-tracing data, we identified 509 transmission chains from 20 provinces in China and estimated the serial interval (SI) and generation interval (GI) of COVID-19 in China. Inspired by different possible values of the time-varying reproduction number for the imported cases and the local cases in China, we divided all transmission events into three subsets: imported (the zeroth generation) infecting 1st-generation locals, 1st-generation locals infecting 2nd-generation locals, and other transmissions among 2+. The corresponding SI (GI) is respectively denoted as [Formula: see text] ([Formula: see text]), [Formula: see text] ([Formula: see text]), and [Formula: see text] ([Formula: see text]). A Bayesian approach with doubly interval-censored likelihood is employed to fit the distribution function of the SI and GI. It was found that the estimated [Formula: see text] , [Formula: see text] , [Formula: see text] , and [Formula: see text] , [Formula: see text] , [Formula: see text]. Thus, overall both SI and GI decrease when generation increases.
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spelling pubmed-78210422021-01-23 Serial Interval and Generation Interval for Imported and Local Infectors, Respectively, Estimated Using Reported Contact-Tracing Data of COVID-19 in China Li, Menghui Liu, Kai Song, Yukun Wang, Ming Wu, Jinshan Front Public Health Public Health The emerging virus, COVID-19, has caused a massive outbreak worldwide. Based on the publicly available contact-tracing data, we identified 509 transmission chains from 20 provinces in China and estimated the serial interval (SI) and generation interval (GI) of COVID-19 in China. Inspired by different possible values of the time-varying reproduction number for the imported cases and the local cases in China, we divided all transmission events into three subsets: imported (the zeroth generation) infecting 1st-generation locals, 1st-generation locals infecting 2nd-generation locals, and other transmissions among 2+. The corresponding SI (GI) is respectively denoted as [Formula: see text] ([Formula: see text]), [Formula: see text] ([Formula: see text]), and [Formula: see text] ([Formula: see text]). A Bayesian approach with doubly interval-censored likelihood is employed to fit the distribution function of the SI and GI. It was found that the estimated [Formula: see text] , [Formula: see text] , [Formula: see text] , and [Formula: see text] , [Formula: see text] , [Formula: see text]. Thus, overall both SI and GI decrease when generation increases. Frontiers Media S.A. 2021-01-08 /pmc/articles/PMC7821042/ /pubmed/33490015 http://dx.doi.org/10.3389/fpubh.2020.577431 Text en Copyright © 2021 Li, Liu, Song, Wang and Wu. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Public Health
Li, Menghui
Liu, Kai
Song, Yukun
Wang, Ming
Wu, Jinshan
Serial Interval and Generation Interval for Imported and Local Infectors, Respectively, Estimated Using Reported Contact-Tracing Data of COVID-19 in China
title Serial Interval and Generation Interval for Imported and Local Infectors, Respectively, Estimated Using Reported Contact-Tracing Data of COVID-19 in China
title_full Serial Interval and Generation Interval for Imported and Local Infectors, Respectively, Estimated Using Reported Contact-Tracing Data of COVID-19 in China
title_fullStr Serial Interval and Generation Interval for Imported and Local Infectors, Respectively, Estimated Using Reported Contact-Tracing Data of COVID-19 in China
title_full_unstemmed Serial Interval and Generation Interval for Imported and Local Infectors, Respectively, Estimated Using Reported Contact-Tracing Data of COVID-19 in China
title_short Serial Interval and Generation Interval for Imported and Local Infectors, Respectively, Estimated Using Reported Contact-Tracing Data of COVID-19 in China
title_sort serial interval and generation interval for imported and local infectors, respectively, estimated using reported contact-tracing data of covid-19 in china
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821042/
https://www.ncbi.nlm.nih.gov/pubmed/33490015
http://dx.doi.org/10.3389/fpubh.2020.577431
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