Fortified Coiled Coils: Enhancing Mechanical Stability with Lactam or Metal Staples

Coiled coils (CCs) are powerful supramolecular building blocks for biomimetic materials, increasingly used for their mechanical properties. Here, we introduce helix‐inducing macrocyclic constraints, so‐called staples, to tune thermodynamic and mechanical stability of CCs. We show that thermodynamic...

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Detalles Bibliográficos
Autores principales: López‐García, Patricia, de Araujo, Aline D., Bergues‐Pupo, Ana E., Tunn, Isabell, Fairlie, David P., Blank, Kerstin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821110/
https://www.ncbi.nlm.nih.gov/pubmed/32940968
http://dx.doi.org/10.1002/anie.202006971

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