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Probing the Conformation States of Neurotensin Receptor 1 Variants by NMR Site‐Directed Methyl Labeling

G protein‐coupled receptors (GPCRs) are key players in mediating signal transduction across the cell membrane. However, due to their intrinsic instability, many GPCRs are not suitable for structural investigations. Various approaches have been developed in recent years to remedy this situation, rang...

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Detalles Bibliográficos
Autores principales: Goba, Inguna, Goricanec, David, Schum, Dominik, Hillenbrand, Matthias, Plückthun, Andreas, Hagn, Franz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821118/
https://www.ncbi.nlm.nih.gov/pubmed/32881260
http://dx.doi.org/10.1002/cbic.202000541

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