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Reprogramming progressive cells display low CAG promoter activity

There is wide variability in the propensity of somatic cells to reprogram into pluripotency in response to the Yamanaka factors. How to segregate these variabilities to enrich for cells of specific traits that reprogram efficiently remains challenging. Here we report that the variability in reprogra...

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Detalles Bibliográficos
Autores principales: Hu, Xiao, Wu, Qiao, Zhang, Jian, Kim, Jonghun, Chen, Xinyue, Hartman, Amaleah A., Eastman, Anna E., Park, In‐Hyun, Guo, Shangqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821215/
https://www.ncbi.nlm.nih.gov/pubmed/33075202
http://dx.doi.org/10.1002/stem.3295