Extracellular clusterin limits the uptake of α‐synuclein fibrils by murine and human astrocytes

The progressive neuropathological damage seen in Parkinson's disease (PD) is thought to be related to the spreading of aggregated forms of α‐synuclein. Clearance of extracellular α‐synuclein released by degenerating neurons may be therefore a key mechanism to control the concentration of α‐synu...

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Detalles Bibliográficos
Autores principales: Filippini, Alice, Mutti, Veronica, Faustini, Gaia, Longhena, Francesca, Ramazzina, Ileana, Rizzi, Federica, Kaganovich, Alice, Roosen, Dorien A., Landeck, Natalie, Duffy, Megan, Tessari, Isabella, Bono, Federica, Fiorentini, Chiara, Greggio, Elisa, Bubacco, Luigi, Bellucci, Arianna, Missale, Mariacristina, Cookson, Mark R., Gennarelli, Massimo, Russo, Isabella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821254/
https://www.ncbi.nlm.nih.gov/pubmed/33045109
http://dx.doi.org/10.1002/glia.23920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821254/
https://www.ncbi.nlm.nih.gov/pubmed/33045109
http://dx.doi.org/10.1002/glia.23920

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