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Germacrene A–A Central Intermediate in Sesquiterpene Biosynthesis
This review summarises known sesquiterpenes whose biosyntheses proceed through the intermediate germacrene A. First, the occurrence and biosynthesis of germacrene A in Nature and its peculiar chemistry will be highlighted, followed by a discussion of 6–6 and 5–7 bicyclic compounds and their more com...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821278/ https://www.ncbi.nlm.nih.gov/pubmed/32442350 http://dx.doi.org/10.1002/chem.202002163 |
| _version_ | 1783639387607662592 |
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| author | Xu, Houchao Dickschat, Jeroen S. |
| author_facet | Xu, Houchao Dickschat, Jeroen S. |
| author_sort | Xu, Houchao |
| collection | PubMed |
| description | This review summarises known sesquiterpenes whose biosyntheses proceed through the intermediate germacrene A. First, the occurrence and biosynthesis of germacrene A in Nature and its peculiar chemistry will be highlighted, followed by a discussion of 6–6 and 5–7 bicyclic compounds and their more complex derivatives. For each compound the absolute configuration, if it is known, and the reasoning for its assignment is presented. |
| format | Online Article Text |
| id | pubmed-7821278 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | John Wiley and Sons Inc. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-78212782021-01-29 Germacrene A–A Central Intermediate in Sesquiterpene Biosynthesis Xu, Houchao Dickschat, Jeroen S. Chemistry Reviews This review summarises known sesquiterpenes whose biosyntheses proceed through the intermediate germacrene A. First, the occurrence and biosynthesis of germacrene A in Nature and its peculiar chemistry will be highlighted, followed by a discussion of 6–6 and 5–7 bicyclic compounds and their more complex derivatives. For each compound the absolute configuration, if it is known, and the reasoning for its assignment is presented. John Wiley and Sons Inc. 2020-09-30 2020-12-23 /pmc/articles/PMC7821278/ /pubmed/32442350 http://dx.doi.org/10.1002/chem.202002163 Text en © 2020 The Authors. Published by Wiley-VCH GmbH This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Reviews Xu, Houchao Dickschat, Jeroen S. Germacrene A–A Central Intermediate in Sesquiterpene Biosynthesis |
| title | Germacrene A–A Central Intermediate in Sesquiterpene Biosynthesis |
| title_full | Germacrene A–A Central Intermediate in Sesquiterpene Biosynthesis |
| title_fullStr | Germacrene A–A Central Intermediate in Sesquiterpene Biosynthesis |
| title_full_unstemmed | Germacrene A–A Central Intermediate in Sesquiterpene Biosynthesis |
| title_short | Germacrene A–A Central Intermediate in Sesquiterpene Biosynthesis |
| title_sort | germacrene a–a central intermediate in sesquiterpene biosynthesis |
| topic | Reviews |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821278/ https://www.ncbi.nlm.nih.gov/pubmed/32442350 http://dx.doi.org/10.1002/chem.202002163 |
| work_keys_str_mv | AT xuhouchao germacreneaacentralintermediateinsesquiterpenebiosynthesis AT dickschatjeroens germacreneaacentralintermediateinsesquiterpenebiosynthesis |