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N-acetylcysteine inhibits atherosclerosis by correcting glutathione-dependent methylglyoxal elimination and dicarbonyl/oxidative stress in the aorta of diabetic mice

In diabetic animal models, high plasma/tissue levels of methylglyoxal (MG) are implicated in atherosclerosis. N-acetylcysteine (NAC) is a cysteine prodrug that replenishes intracellular glutathione (GSH) levels, which can increase the elimination of MG in diabetes mellitus (DM). The present study in...

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Detalles Bibliográficos
Autores principales:	Fang, Xin, Liu, Lihua, Zhou, Shaoqiong, Zhu, Mengen, Wang, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821347/ https://www.ncbi.nlm.nih.gov/pubmed/33495825 http://dx.doi.org/10.3892/mmr.2021.11840

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