Multi-Targeted Anticancer Activity of Imidazolate Phosphane Gold(I) Compounds by Inhibition of DHFR and TrxR in Breast Cancer Cells

A class of phosphane gold(I) compounds, made of azoles and phosphane ligands, was evaluated for a screening on the regards of Breast Cancer cell panels (BC). The compounds possess N-Au-P or Cl-Au-P bonds around the central metal, and they differ for the presence of aprotic or protic polar groups in...

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Detalles Bibliográficos
Autores principales: Galassi, Rossana, Luciani, Lorenzo, Gambini, Valentina, Vincenzetti, Silvia, Lupidi, Giulio, Amici, Augusto, Marchini, Cristina, Wang, Junbiao, Pucciarelli, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821381/
https://www.ncbi.nlm.nih.gov/pubmed/33490036
http://dx.doi.org/10.3389/fchem.2020.602845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821381/
https://www.ncbi.nlm.nih.gov/pubmed/33490036
http://dx.doi.org/10.3389/fchem.2020.602845

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