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Efficacy of Indocyanine Green Fluorescence Angiography in Preventing Anastomotic Leakage After McKeown Minimally Invasive Esophagectomy
BACKGROUND: Indocyanine green (ICG) fluorescence angiography (FA) was introduced to provide real-time intraoperative evaluation of the vascular perfusion of the gastric conduit during esophagectomy. However, its efficacy has not yet been proven. The aim of this study was to assess the usefulness of...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821423/ https://www.ncbi.nlm.nih.gov/pubmed/33489925 http://dx.doi.org/10.3389/fonc.2020.619822 |
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author | Luo, Rao-Jun Zhu, Zi-Yi He, Zheng-Fu Xu, Yong Wang, Yun-Zheng Chen, Ping |
author_facet | Luo, Rao-Jun Zhu, Zi-Yi He, Zheng-Fu Xu, Yong Wang, Yun-Zheng Chen, Ping |
author_sort | Luo, Rao-Jun |
collection | PubMed |
description | BACKGROUND: Indocyanine green (ICG) fluorescence angiography (FA) was introduced to provide real-time intraoperative evaluation of the vascular perfusion of the gastric conduit during esophagectomy. However, its efficacy has not yet been proven. The aim of this study was to assess the usefulness of ICG-FA in the reduction of the rates of anastomotic leakage (AL) in McKeown minimally invasive esophagectomy (MIE). METHODS: From June 2017 to December 2019, patients aged between 18 and 80 years with esophageal carcinoma were enrolled in the study and each patient underwent McKeown MIE. Patients were divided into two groups, those with or without ICG-FA. The patient demographics and perioperative outcomes were comparable between the two groups. The primary outcome was the rate of AL. RESULTS: A total of 192 patients were included: 86 in the ICG-FA group and 106 in the non-ICG-FA group. Overall, 12 patients (6.3%) had AL; the rate of AL was 10.4% in the non-ICG-FA group, which was significantly higher than the 1.2% in the ICG-FA group. CONCLUSIONS: ICG-FA has the potential to reduce the rate of AL in McKeown MIE. |
format | Online Article Text |
id | pubmed-7821423 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-78214232021-01-23 Efficacy of Indocyanine Green Fluorescence Angiography in Preventing Anastomotic Leakage After McKeown Minimally Invasive Esophagectomy Luo, Rao-Jun Zhu, Zi-Yi He, Zheng-Fu Xu, Yong Wang, Yun-Zheng Chen, Ping Front Oncol Oncology BACKGROUND: Indocyanine green (ICG) fluorescence angiography (FA) was introduced to provide real-time intraoperative evaluation of the vascular perfusion of the gastric conduit during esophagectomy. However, its efficacy has not yet been proven. The aim of this study was to assess the usefulness of ICG-FA in the reduction of the rates of anastomotic leakage (AL) in McKeown minimally invasive esophagectomy (MIE). METHODS: From June 2017 to December 2019, patients aged between 18 and 80 years with esophageal carcinoma were enrolled in the study and each patient underwent McKeown MIE. Patients were divided into two groups, those with or without ICG-FA. The patient demographics and perioperative outcomes were comparable between the two groups. The primary outcome was the rate of AL. RESULTS: A total of 192 patients were included: 86 in the ICG-FA group and 106 in the non-ICG-FA group. Overall, 12 patients (6.3%) had AL; the rate of AL was 10.4% in the non-ICG-FA group, which was significantly higher than the 1.2% in the ICG-FA group. CONCLUSIONS: ICG-FA has the potential to reduce the rate of AL in McKeown MIE. Frontiers Media S.A. 2021-01-08 /pmc/articles/PMC7821423/ /pubmed/33489925 http://dx.doi.org/10.3389/fonc.2020.619822 Text en Copyright © 2021 Luo, Zhu, He, Xu, Wang and Chen http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Oncology Luo, Rao-Jun Zhu, Zi-Yi He, Zheng-Fu Xu, Yong Wang, Yun-Zheng Chen, Ping Efficacy of Indocyanine Green Fluorescence Angiography in Preventing Anastomotic Leakage After McKeown Minimally Invasive Esophagectomy |
title | Efficacy of Indocyanine Green Fluorescence Angiography in Preventing Anastomotic Leakage After McKeown Minimally Invasive Esophagectomy |
title_full | Efficacy of Indocyanine Green Fluorescence Angiography in Preventing Anastomotic Leakage After McKeown Minimally Invasive Esophagectomy |
title_fullStr | Efficacy of Indocyanine Green Fluorescence Angiography in Preventing Anastomotic Leakage After McKeown Minimally Invasive Esophagectomy |
title_full_unstemmed | Efficacy of Indocyanine Green Fluorescence Angiography in Preventing Anastomotic Leakage After McKeown Minimally Invasive Esophagectomy |
title_short | Efficacy of Indocyanine Green Fluorescence Angiography in Preventing Anastomotic Leakage After McKeown Minimally Invasive Esophagectomy |
title_sort | efficacy of indocyanine green fluorescence angiography in preventing anastomotic leakage after mckeown minimally invasive esophagectomy |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821423/ https://www.ncbi.nlm.nih.gov/pubmed/33489925 http://dx.doi.org/10.3389/fonc.2020.619822 |
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