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Chronic exposure to IL-6 induces a desensitized phenotype of the microglia

BACKGROUND: When the homeostasis of the central nervous system (CNS) is altered, microglial cells become activated displaying a wide range of phenotypes that depend on the specific site, the nature of the activator, and particularly the microenvironment generated by the lesion. Cytokines are importa...

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Detalles Bibliográficos
Autores principales: Recasens, Mireia, Almolda, Beatriz, Pérez-Clausell, Jeús, Campbell, Iain L., González, Berta, Castellano, Bernardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821504/
https://www.ncbi.nlm.nih.gov/pubmed/33482848
http://dx.doi.org/10.1186/s12974-020-02063-1