Assessing the clinical utility of genetic risk scores for targeted cancer screening

BACKGROUND: Genome-wide association studies have identified thousands of disease-associated single nucleotide polymorphisms (SNPs). A subset of these SNPs may be additively combined to generate genetic risk scores (GRSs) that confer risk for a specific disease. Although the clinical validity of GRSs...

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Detalles Bibliográficos
Autores principales: Conran, Carly A., Shi, Zhuqing, Resurreccion, William Kyle, Na, Rong, Helfand, Brian T., Genova, Elena, Zheng, Siqun Lilly, Brendler, Charles B., Xu, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821544/
https://www.ncbi.nlm.nih.gov/pubmed/33482857
http://dx.doi.org/10.1186/s12967-020-02699-w

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