Loss of Fas signaling in fibroblasts impairs homeostatic fibrosis resolution and promotes persistent pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive, irreversible fibrotic disease of the distal lung alveoli that culminates in respiratory failure and reduced lifespan. Unlike normal lung repair in response to injury, IPF is associated with the accumulation and persistence of fibroblasts and myof...

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Detalles Bibliográficos
Autores principales: Redente, Elizabeth F., Chakraborty, Sangeeta, Sajuthi, Satria, Black, Bart P., Edelman, Ben L., Seibold, Max A., Riches, David W.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821600/
https://www.ncbi.nlm.nih.gov/pubmed/33290280
http://dx.doi.org/10.1172/jci.insight.141618

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