Diagnostic accuracy of a liquid chromatography-tandem mass spectrometry assay in small hair samples for rifampin-resistant tuberculosis drug concentrations in a routine care setting

BACKGROUND: Treatment monitoring of drug-resistant tuberculosis (DR-TB) in resource-limited settings is challenging. We developed a multi-analyte assay for eleven anti-TB drugs in small hair samples as an objective metric of drug exposure. METHODS: Small hair samples were collected from participants...

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Detalles Bibliográficos
Autores principales: Metcalfe, John, Bacchetti, Peter, Esmail, Ali, Reckers, Andrew, Aguilar, David, Wen, Anita, Huo, Shu, Muyindike, Winnie R., Hahn, Judith A., Dheda, Keertan, Gandhi, Monica, Gerona, Roy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821664/
https://www.ncbi.nlm.nih.gov/pubmed/33482745
http://dx.doi.org/10.1186/s12879-020-05738-5

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