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Deficiency of Inositol Monophosphatase Activity Decreases Phosphoinositide Lipids and Enhances TRPV1 Function In Vivo

Membrane remodeling by inflammatory mediators influences the function of sensory ion channels. The capsaicin- and heat-activated transient receptor potential vanilloid 1 (TRPV1) channel contributes to neurogenic inflammation and pain hypersensitivity, in part because of its potentiation downstream o...

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Detalles Bibliográficos
Autores principales: Caires, Rebeca, Bell, Briar, Lee, Jungsoo, Romero, Luis O., Vásquez, Valeria, Cordero-Morales, Julio F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821860/
https://www.ncbi.nlm.nih.gov/pubmed/33239401
http://dx.doi.org/10.1523/JNEUROSCI.0803-20.2020