BRAF inhibition protects against hearing loss in mice

Hearing loss caused by noise, aging, antibiotics, and chemotherapy affects 10% of the world population, yet there are no Food and Drug Administration (FDA)-approved drugs to prevent it. Here, we screened 162 small-molecule kinase-specific inhibitors for reduction of cisplatin toxicity in an inner ea...

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Detalles Bibliográficos
Autores principales: Ingersoll, Matthew A., Malloy, Emma A., Caster, Lauryn E., Holland, Eva M., Xu, Zhenhang, Zallocchi, Marisa, Currier, Duane, Liu, Huizhan, He, David Z.Z., Min, Jaeki, Chen, Taosheng, Zuo, Jian, Teitz, Tal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821884/
https://www.ncbi.nlm.nih.gov/pubmed/33268358
http://dx.doi.org/10.1126/sciadv.abd0561

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