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Mga safeguards embryonic stem cells from acquiring extraembryonic endoderm fates

Polycomb group (PcG) proteins form multiprotein complexes that affect stem cell identity and fate decisions by still largely unexplored mechanisms. Here, by performing a CRISPR-based loss-of-function screen in embryonic stem cells (ESCs), we identify PcG gene Mga involved in the repression of endode...

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Detalles Bibliográficos
Autores principales:	Qin, Jinzhong, Wang, Congcong, Zhu, Yaru, Su, Ting, Dong, Lixia, Huang, Yikai, Hao, Kunying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821913/ https://www.ncbi.nlm.nih.gov/pubmed/33523934 http://dx.doi.org/10.1126/sciadv.abe5689

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