Spatial Structure and Activity of Synthetic Fragments of Lynx1 and of Nicotinic Receptor Loop C Models

Lynx1, membrane-bound protein co-localized with the nicotinic acetylcholine receptors (nAChRs) and regulates their function, is a three-finger protein (TFP) made of three β-structural loops, similarly to snake venom α-neurotoxin TFPs. Since the central loop II of α-neurotoxins is involved in binding...

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Detalles Bibliográficos
Autores principales: Mineev, Konstantin S., Kryukova, Elena V., Kasheverov, Igor E., Egorova, Natalia S., Zhmak, Maxim N., Ivanov, Igor A., Senko, Dmitry A., Feofanov, Alexey V., Ignatova, Anastasia A., Arseniev, Alexander S., Utkin, Yuri N., Tsetlin, Victor I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821949/
https://www.ncbi.nlm.nih.gov/pubmed/33374963
http://dx.doi.org/10.3390/biom11010001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821949/
https://www.ncbi.nlm.nih.gov/pubmed/33374963
http://dx.doi.org/10.3390/biom11010001

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