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Osteopontin regulates type I collagen fibril formation in bone tissue()

Osteopontin (OPN) is a non-collagenous protein involved in biomineralization of bone tissue. Beyond its role in biomineralization, we show that osteopontin is essential to the quality of collagen fibrils in bone. Transmission electron microscopy revealed that, in Opn(−/−) tissue, the organization of...

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Detalles Bibliográficos
Autores principales: Depalle, Baptiste, McGilvery, Catriona M., Nobakhti, Sabah, Aldegaither, Nouf, Shefelbine, Sandra J., Porter, Alexandra E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821990/
https://www.ncbi.nlm.nih.gov/pubmed/32344173
http://dx.doi.org/10.1016/j.actbio.2020.04.040