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Osteopontin regulates type I collagen fibril formation in bone tissue()
Osteopontin (OPN) is a non-collagenous protein involved in biomineralization of bone tissue. Beyond its role in biomineralization, we show that osteopontin is essential to the quality of collagen fibrils in bone. Transmission electron microscopy revealed that, in Opn(−/−) tissue, the organization of...
Autores principales: | Depalle, Baptiste, McGilvery, Catriona M., Nobakhti, Sabah, Aldegaither, Nouf, Shefelbine, Sandra J., Porter, Alexandra E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821990/ https://www.ncbi.nlm.nih.gov/pubmed/32344173 http://dx.doi.org/10.1016/j.actbio.2020.04.040 |
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