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Empagliflozin Regulates the AdipoR1/p-AMPK/p-ACC Pathway to Alleviate Lipid Deposition in Diabetic Nephropathy

BACKGROUND: Abnormal lipid deposition in the progress of diabetic nephropathy (DN) plays an important role in a number of studies that have shown that SGLT2 inhibitor (SGLT2i) empagliflozin plays an important role in lipid metabolism, but its mechanism is still unclear. METHODS: We aimed to explore...

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Detalles Bibliográficos
Autores principales: Zhang, Zhiqin, Ni, Lihua, Zhang, Lian, Zha, Dongqing, Hu, Chun, Zhang, Lingli, Feng, Huiling, Wei, Xiaobao, Wu, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822229/
https://www.ncbi.nlm.nih.gov/pubmed/33500643
http://dx.doi.org/10.2147/DMSO.S289712