Association between tobacco substance usage and a missense mutation in the tumor suppressor gene P53 in the Saudi Arabian population

The tumor suppressor gene TP53 and its downstream genes P21 and MDM2 play crucial roles in combating DNA damage at the G(1)/S cell cycle checkpoint. Polymorphisms in these genes can lead to the development of various diseases. This study was conducted to examine a potential association between tobac...

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Detalles Bibliográficos
Autores principales: Almutairi, Mikhlid H., Almutairi, Bader O., Alrubie, Turki M., Alharbi, Sultan N., Parine, Narasimha R., Alrefaei, Abdulwahed F., Aldeailej, Ibrahim, Alamri, Abdullah, Semlali, Abdelhabib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822264/
https://www.ncbi.nlm.nih.gov/pubmed/33481818
http://dx.doi.org/10.1371/journal.pone.0245133

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